Pure Quillaic Acid (CAS 631-01-6) | HPLC≥98%/NMR Validated | Bulk Sourcing

🌿 Quillaic Acid (CAS: 631-01-6) 

⚙️ Chemical & Physical Properties

🧪 Biological Activities & Applications

Validated Functions

1. Analgesic Effects:

   • Exhibits dose-dependent pain relief in preclinical models.

2. Phytochemical Reference:

   • Used as a high-purity standard (≥98%) for quality control in herbal extracts and saponin analysis.

3. Research Applications:

   • Pharmacology: Mechanistic studies on triterpenoid bioactivity.

   • Natural Product Chemistry: Isolation and structural validation of saponins.

📦 Supply Specifications & Packaging

• Purity validated by HPLC-DAD/ELSD, NMR, and MS.

• Custom packaging (e.g., β-cyclodextrin complexes) available for solubility enhancement.

⚠️ Safety & Handling

• Toxicity:

  • Acute oral LD₅₀ (rat) >1,000 mg/kg; non-genotoxic (OECD 471 compliant).

• Hazards:

  • Skin/Irritant: Causes skin and eye damage; use PPE (gloves, goggles).

  • Inhalation Risk: Avoid dust formation6.

• Regulatory Compliance:

  • EINECS: 211-149-8; heavy metals controlled (As <0.1 ppm, Pb <0.2 ppm; ICP-MS).

🧪 Application Notes for Researchers

1. Solubility Optimization:

   • For cell-based assays: Dissolve in DMSO (up to 180.8 mM), then dilute in buffer.

2. Analytical Methods:

   • HPLC Conditions: C18 column, gradient MeCN/H₂O + 0.1% formic acid, detection at 210 nm.

   • Structural Confirmation: ¹H/¹³C NMR (CDCl₃ or pyridine-d₅).

3. Stability:

   • Stable for >24 months at 2–8°C; degrades in alkaline conditions (pH >7).

💎 Key Advantages for Industrial Use

• Green Extraction: Supercritical technology (yield ≥96%, solvent-free).

• Batch Consistency: Rigorous QC via HPLC/MS/NMR ensures reproducibility.

• Multi-Format Flexibility: Suitable for oral, topical, and injectable formulations (via solubility modifiers).

Summary: Quillaic acid (CAS 631-01-6) is a high-value triterpenoid for analgesic research and phytochemical standardization. Its validated purity (≥98%), safety profile, and scalable supply make it ideal for academic and industrial R&D. For batch-specific COA or custom formulations, contact suppliers directly. 🔬